Seizure disorder medication oral contraceptive

In addition, hormonal contraception can have a bidirectional interaction with some AEDs, which can result in loss of seizure control or toxicity. Several contraceptive options that do not interact with AEDs, such as barrier and long-acting forms, are available. High dosages of emergency contraception and oral regimens also may be considered. Intervention by the pharmacist can include making recommendations about contraceptive options, advising on therapeutic drug concentration monitoring, and increasing awareness among patients and prescribers. Hormonal contraception can have a bidirectional interaction with some antiepileptic drugs AEDs , which can lead to loss of seizure control or toxicity. Alternative contraception recommendations are addressed so that more effective forms of birth control can be discussed with patients and providers.
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Birth control pills may increase risk of seizures

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Birth control pills may increase risk of seizures -- ScienceDaily

This article has been corrected. See Expert Rev Neurother. Abstract Introduction Hormonal contraceptives are used by over million people worldwide. Recently, there has been an emerging interest in studying the potential impact of oral contraceptives OCs on certain neurological conditions. It has been suspected for some time that hormonal birth control increases seizure activity in women with epilepsy, but there is little supportive data. Areas Covered Literature from PubMed and online sources was analyzed with respect to hormonal contraception and epilepsy or seizures. New evidence indicates that OCs can cause an increase in seizures in women with epilepsy.
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Contraception for women with epilepsy: counseling, choices, and concerns

Do antiepileptic drugs affect oral contraceptive effectiveness? Evidence-Based Answer We found no studies that measure, or even estimate, any increase in pregnancy rates in women taking antiepileptic drugs. Antiepileptic drugs known to induce the hepatic cytochrome P CYP isoenzyme cause decreased sex hormone levels in women taking oral contraceptives, raising the potential for decreased effectiveness of oral contraceptives and increased risk of unplanned pregnancy.
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By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. This is worrying, given the increased occurrence of obstetrical complications in WWE, including the risk of seizures and their possible consequences for both the mother and the unborn child.
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